Intravenous Ribavirin Treatment for Severe Adenovirus Disease in Immunocompromised Children -- Gavin and Katz 110 (1): 9 -- Pediatrics
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Intravenous ribavirin treatment for severe adenovirus disease in immunocompromised children.
BACKGROUND Adenovirus is an important cause of morbidity and mortality in the immunocompromised host. The incidence of severe adenovirus disease in pediatrics is increasing in association with growing numbers of immunocompromised children, where case fatality rates as high as 50% to 80% have been reported. There are no approved antiviral agents with proven efficacy for the treatment of severe a...
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Background Kawasaki disease (KD) is the second most common childhood vasculitis and one of the main causes of acquired heart disease in children. Recent work focuses on the early diagnostic importance of those risk factors that indicate resistance to intravenous immunoglobulin (IVIG) treatment. The objectives of this study were to identify clinical, laboratory and/or instrumental factors that c...
متن کاملRespiratory Tract Infections Due to Human Metapneumovirus in Immunocompromised Children
BACKGROUND The clinical presentation and management of human metapneumovirus (hMPV) infections in immunocompromised children is not well understood. METHODS We performed a retrospective evaluation of pediatric patients with laboratory-confirmed hMPV infections and underlying hematologic malignancy, solid tumors, solid organ transplant, rheumatologic disease, and/or receipt of chronic immunosu...
متن کاملCurrent management of parainfluenza pneumonitis in immunocompromised patients: a review
Parainfluenza viruses (PIV) are common respiratory viruses that belong to the Paramyxoviridae family. PIV infection can lead to a wide variety of clinical syndromes ranging from mild upper respiratory illness to severe pneumonia. Severe disease can be seen in elderly or chronically ill persons and may be fatal in persons with compromised immune systems, particularly children with severe combine...
متن کاملAdenovirus pneumonitis successfully treated with intravenous ribavirin.
Adenovirus infections are a frequent cause of severe complications in the post allogeneic bone marrow transplantation period, and to date, no established form of treatment exists. We report the case of an autologous bone marrow transplant recipient who developed adenovirus pneumonitis which was successfully treated with intravenous ribavirin.
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تاریخ انتشار 2005